Biostatistics
Learning Objectives By Lesson
1-Sensitivity & Specificity
• Define and differentiate sensitivity and specificity
• Calculate sensitivity and specificity based on 2x2 table or its equivalent
• Understand how to employ sensitivity and specificity to rule in/out disease
2-Negative & Positive Predictive Values
• Define and differentiate negative predictive value (NPV) and positive predictive value (PPV)
• Calculate negative predictive value (NPV) and positive predictive value (PPV) based on 2x2 table or its equivalent
• Understand how to use negative predictive value (NPV) and positive predictive value (PPV) to evaluate diagnostic tests
3-Likelihood Ratio & Post-Test Probability
• Define and differentiate positive and negative likelihood ratios
• Calculate positive and negative likelihood ratios based on 2x2 table or its equivalent
• Understand how to employ different diagnostic testing parameters in clinical practice
• Describe the difference between probability and odds
4-Precision & Accuracy
• Define and differentiate between precision and accuracy
• Understand the different synonyms that can be used to refer to precision and accuracy
• Describe different types of error that can be associated with precision and accuracy
5-Study Types
• Define and differentiate between various study types
• Know the expected outcome measures based on study type
• Understand and interpret receiver operating characteristic (ROC) curve
• Be able to compare between different points on the receiver operating characteristic (ROC) curve in terms of sensitivity and specificity as well as between different diagnostic tests
• Understand how the changes in cutoff are expected to affect sensitivity and specificity of a diagnostic test
7-Quantifying Risk (Part 1)
• Understand how to quantify risk using odds ratio and relative risk
• Define and differentiate between odds ratio and relative risk
• Calculate odds ratio and relative risk when given a 2x2 table or its equivalent
8-Prevalence & Incidence
• Define and differentiate between prevalence and incidence
• Learn how to calculate prevalence and incidence
• Understand how different factors can affect prevalence and incidence
Contributors: Mohamad S. Alabdaljabar, MBBS; Anas Idris, MBBS; Khaled Abdullah, MBBS; Bushra Hafez, MBBS; Anas Alkhabaz, MBBS
Last updated:
January 2023.
Progress

Instructors
GCU Education Team
Physician Educators