Biostatistics

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Learning Objectives By Lesson
1-Sensitivity & Specificity

Define and differentiate sensitivity and specificity
Calculate sensitivity and specificity based on 2x2 table or its equivalent
Understand how to employ sensitivity and specificity to rule in/out disease

2-Negative & Positive Predictive Values

Define and differentiate negative predictive value (NPV) and positive predictive value (PPV)
Calculate negative predictive value (NPV) and positive predictive value (PPV) based on 2x2 table or its equivalent
Understand how to use negative predictive value (NPV) and positive predictive value (PPV) to evaluate diagnostic tests

3-Likelihood Ratio & Post-Test Probability

Define and differentiate positive and negative likelihood ratios
Calculate positive and negative likelihood ratios based on 2x2 table or its equivalent
Understand how to employ different diagnostic testing parameters in clinical practice
Describe the difference between probability and odds

4-Precision & Accuracy

Define and differentiate between precision and accuracy
Understand the different synonyms that can be used to refer to precision and accuracy
Describe different types of error that can be associated with precision and accuracy

5-Study Types

Define and differentiate between various study types
Know the expected outcome measures based on study type
Understand the advantages and possible disadvantages of different study types

6-Receiver Operating Characteristic (ROC) Curve

Understand and interpret receiver operating characteristic (ROC) curve
Be able to compare between different points on the receiver operating characteristic (ROC) curve in terms of sensitivity and specificity as well as between different diagnostic tests
Understand how the changes in cutoff are expected to affect sensitivity and specificity of a diagnostic test

7-Quantifying Risk (Part 1)

Understand how to quantify risk using odds ratio and relative risk
Define and differentiate between odds ratio and relative risk
Calculate odds ratio and relative risk when given a 2x2 table or its equivalent

8-Prevalence & Incidence

Define and differentiate between prevalence and incidence
Learn how to calculate prevalence and incidence
Understand how different factors can affect prevalence and incidence

Contributors: Mohamad S. Alabdaljabar, MBBS; Anas Idris, MBBS; Khaled Abdullah, MBBS; Bushra Hafez, MBBS; Anas Alkhabaz, MBBS
Last updated: January 2023.

1 - Sensitivity & Specificity

Duration: 6:38
2 - Negative & Positive Predictive Values

Duration: 7:43
3 - Likelihood Ratio & Post-Test Probability

Duration: 10:16
4 - Precision & Accuracy

Duration: 4:37
5 - Study Types

Duration: 5:32
6 - Receiver Operating Characteristic (ROC) Curve

Duration: 6:45
7 - Quantifying Risk (Part 1)

Duration: 6:21
8 - Prevalence & Incidence

Duration: 4:32

Progress

Instructors

GCU Education Team
Physician Educators